Percocet 10/325mg Tablets

Percocet 10/325mg Tablets: Safety Information

Percocet is a combination prescription medication containing two active ingredients: oxycodone (an opioid pain reliever) and acetaminophen (a non-opioid pain reliever and fever reducer). It is used for the management of moderate to severe pain when other treatments are inadequate.

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1. 🧪 Drug Profile

• Oxycodone Hydrochloride: 10mg — A semi-synthetic opioid agonist.

• Acetaminophen: 325mg — A non-opioid analgesic.

• Purpose: Provides relief through two mechanisms: opioid action in the central nervous system and peripheral pain reduction via acetaminophen.

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2. ⚠️ Critical Risks & Black Box Warnings

• ADDICTION, ABUSE, AND MISUSE: Oxycodone exposes users to risks of addiction, abuse, and misuse, which can lead to overdose and death.

• LIFE-THREATENING RESPIRATORY DEPRESSION: Serious, life-threatening, or fatal respiratory depression may occur.

• ACCIDENTAL INGESTION: Accidental consumption of even one dose, especially by a child, can result in a fatal overdose.

• ACETAMINOPHEN-RELATED HEPATOTOXICITY: Acetaminophen can cause acute liver failure, sometimes requiring liver transplant or resulting in death.

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3. 🚨 Critical Safety Information

• Do NOT exceed recommended dosage: Taking more than 4,000mg of acetaminophen per day can cause severe liver damage.

• Avoid alcohol: Alcohol consumption increases the risk of liver toxicity and enhances CNS depression.

• Do NOT combine with other CNS depressants:

  • Benzodiazepines (e.g., Xanax, Valium)

  • Other opioids

  • Sedatives, tranquilizers, or sleep aids

• Swallow whole: Do not crush, chew, or dissolve tablets—this can lead to rapid release and absorption of a potentially fatal dose.

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4. ✅ Safe Use Guidelines (For Prescribed Patients Only)

• Take exactly as prescribed—do not increase dose or frequency.

• Use the lowest effective dose for the shortest duration possible.

• Store securely in a locked container to prevent misuse or accidental ingestion.

• Do not stop abruptly—taper under medical supervision to avoid withdrawal symptoms.

• Recognize overdose signs:

  • Slow or stopped breathing

  • Extreme drowsiness or unresponsiveness

  • Pinpoint pupils

  • Cold, clammy skin

How to take Percocet?

Percocet is a dangerous and highly addictive medication that can deteriorate your health even more or make you a drug addict if taken inappropriately.

Take your medicine as prescribed by your doctor and follow all the necessary directions and instructions as given on the medicine or prescription label. We also advise you to tell your doctor if you are not observing any improvement in your health condition.

Percocet dosage

Percocet is an effective medication for treating moderate to severe pain. However, it is a dangerous medication; therefore, it is advisable to consult your doctor for the correct and suitable Percocet dosage.

Your doctor will examine you thoroughly before prescribing you suitable Percocet dosages. Doctors generally consider the following factors before prescribing you appropriate medicine dosages:

• Age of the patient
• Weight of the patient
• The medical condition of the patient

The following are the usual Percocet dosage that your doctor can prescribe you:

Dosage for treating pain

In the form of oral tablets with the strength of 2.5 mg/325 mg

• For adults

One to two Percocet tablets after every six hours or as and when required

• For children

Using Percocet for treating children is not recommended. In the form of oral tablets with the strength of 5 mg/325 mg

• For adults

One Percocet tablet orally, after every six hours or as and when required.

• For children

Using Percocet for treating children is not recommended. In the form of oral tablets with the strength of 7.5 mg/325 mg

• For adults

One Percocet tablet orally, after every six hours or as and when required.

• For children

Using Percocet for treating children is not recommended. In the form of oral tablets with the strength of 10 mg/325 mg

• For adults

One Percocet tablet orally, after every six hours or as and when required.

• For children

Using Percocet for treating children is not recommended.

Overdose

Being an opioid pain medication, Percocet is an effective medication used for reducing pain signals. However, it may cause an overdose if taken in excess.

Observe your health; you may experience the following life-threatening symptoms in the case of Percocet overdose:

• Nausea or vomiting
• Unusual sweating
• Drowsiness or dizziness
• Pinpoint pupils
• Slow or shallow breathing
• Breathlessness

To overcome these fatal overdose symptoms, you should consult your doctor ASAP if an overdose happens. You can also seek emergency medical help by calling the poison helpline at 1-800-222-1222.

What to avoid while using Percocet?

Percocet can impair your thought process and cause dizziness or drowsiness. Therefore, it is advisable to avoid driving and performing any other activities that can cause severe injuries or accidents.

Avoid taking herbal products, vitamins, and other nutritional supplements simultaneously with Percocet. They can dangerously interact with the medicine. Please consult your doctor before taking any other medicine containing acetaminophen.

Taking these medicines all together may result in an overdose.

Percocet side effects

Percocet is one of the effective medicine for treating moderate to severe pain; however, it can cause the following side effects:

• Dizziness or drowsiness
• Tiredness
• Headaches
• Constipation
• Nausea or vomiting
• Pain in the stomach
• Blurred vision
• Itchiness
• Redness in the eyes
• Flushing
• Extreme mood swings
• Dry mouth

It is obvious to experience these mild side effects after using Percocet, and you should not worry too much about them unless they are bothering you too much.

However, it is necessary to consult your doctor if these mild side effects are unbearable or making your life too complicated. Please stop taking Percocet and seek emergency medical assistance ASAP if you experience the following health issues while taking medicine:

• Noisy breathing
• Sighing
• Slow or shallow breathing
• Sleep apnea (breathing that stops while sleeping)
• Slow heart rate
• Weak pulses
• Cold and clammy skin
• Lightheadedness
• Weakness or tiredness
• Fever
• Unusual bruising or bleeding
• Confusion
• Mood swings
• Behavioral disorder
• Seizures or convulsions
• Difficulty in urination
• Nausea or vomiting
• Loss of appetite
• Dizziness
• Symptoms of the damaged liver such as pain in the upper stomach, nausea, tiredness, loss of appetite, dark-colored urine, clay-colored stools, jaundice
• High serotonin level in the body resulting in diarrhea, vomiting, agitation, hallucination, fever, sweating, nausea, or vomiting, sweating, shivering, fast heart rate, stiff muscles, twitching in the muscles
• Infertility (both in men and women)
• Any other severe allergic reaction to the medicine

What drugs can interact with Percocet?

Percocet can dangerously interact with the following medicines and can adversely affect your health and cause death as well:

• Asthma or COPD medications
• Medicines for motion sickness
• Narcotic medications
• Opioids pain medication
• Cough medicines
• Any sedative medication such as diazepam, Xanax, etc
• Sleeping pills
• Drugs affecting the serotonin level in the body
• Medicines to treat mental illness
• Anti-anxiety medication
• Antidepressant

As their interaction can be fatal, it is advisable to take advice from your doctor before starting the treatment if you take these medicines or any other over-the-counter medicines. In addition to this, you should also inform your doctor if you are taking the following medicines:

• Antibiotic medicines
• Antifungal medications
• Heart or blood pressure medicines
• Seizure medication
• Medicines to treat HIV
• Medicines to treat hepatitis C
• Cold or allergy medicines