Percocet 7.5/500mg Tablets: Critical Safety Alert Percocet is a combination prescription medication containing oxycodone (an opioid pain reliever) and acetaminophen (a non-opioid pain reliever). The 7.5/500mg strength contains a higher dose of acetaminophen, which significantly increases the risk of severe liver damage. 1. 🧪 Drug Profile Oxycodone Hydrochloride: 7.5mg — A semi-synthetic opioid agonist. Acetaminophen: 500mg — Higher than standard dose (typical Percocet contains 325mg). Purpose: Management of moderate to severe pain (short-term [...]