Mescaline Powder (200mg): Safety and Information Guide
Mescaline is a naturally occurring psychedelic alkaloid found in specific cacti, such as peyote (Lophophora williamsii) and San Pedro (Echinopsis pachanoi). In powdered form, it is typically consumed orally. A 200mg dose is considered a moderate to strong dose, capable of producing a full psychedelic experience. Below is a safety-focused overview:
1. ⚠️ Dosage and Potency
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200mg is a common threshold dose:
Effects are dose-dependent:-
Light dose: 100–200mg (mild euphoria, enhanced senses).
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Moderate dose: 200–300mg (full psychedelic experience).
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Strong dose: 300–500mg (intense, potentially overwhelming effects).
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Purity matters:
Illicit mescaline powder may be adulterated with other substances (e.g., amphetamines, other phenethylamines) or may not be mescaline at all.
2. 🧠 Expected Effects
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Onset and Duration:
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Onset: 60–90 minutes (oral ingestion).
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Peak: 4–6 hours.
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Total Duration: 10–14 hours.
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Psychological Effects:
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Euphoria, emotional openness, and visual enhancements (e.g., brighter colors, mild patterns).
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Introspection, spiritual insights, and altered thought processes.
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At higher doses, more intense hallucinations and ego softening.
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Physical Effects:
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Nausea and vomiting (common during the first hour).
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Increased heart rate, pupil dilation, and elevated body temperature.
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3. 🚨 Critical Risks
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Nausea and discomfort:
Mescaline is known for causing initial gastrointestinal distress (vomiting, diarrhea). -
Psychological distress:
High doses may lead to anxiety, paranoia, or confusion, especially in unsuitable settings. -
Cardiovascular effects:
Increased heart rate and blood pressure may risk individuals with pre-existing conditions. -
Adulterants:
Powder sold as mescaline may contain harmful substitutes (e.g., NBOMe, DOM) or stimulants.
4. 🩹 Harm Reduction Strategies
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Test your substance:
Use a reagent test kit (e.g., Marquis reagent) to verify the presence of mescaline. -
Start low:
If new to mescaline, consider starting with 100–150mg to assess sensitivity. -
Manage nausea:
Consume on an empty stomach or use ginger/anti-nausea remedies. -
Set and setting:
Use in a safe, comfortable environment with a sober sitter. Avoid public or stressful settings. -
Hydrate:
Drink water to avoid dehydration, but avoid overhydration. -
Avoid mixing:
Do not combine with alcohol, stimulants, or other psychedelics.
5. ⚖️ Legal Status
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Mescaline is a Schedule I controlled substance in the U.S. and many other countries.
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Exceptions exist for religious use (e.g., Native American Church with peyote).
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Possession, sale, or distribution is illegal and punishable by law.









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